Once the presence of inflammatory arthritis is recognized, other arthritis diagnoses (lupus, psoriatic arthritis, spondyloarthritis, among others) are ruled out and finally the risk of developing persistent and / or erosive arthritis is evaluated, 5 considering patients with early RA those with symmetrical polyarthritis and persistent associated with presence of rheumatoid factor (FR) blood and / or anti-citrulline antibodies.
Although the detection of RF has been the most important serological tool for the diagnosis of RA, its sensitivity and specificity in the established disease are 60% (25-95%) and 79% (31-95%) Flekosteel, respectively.
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